-
From Marker Genes to Whole-Community DNA: A Comprehensive Comparison of Amplicon and Shotgun Metagenomic Sequencing
From Marker Genes to Whole-Community DNA: A Comprehensive Comparison of Amplicon and Shotgun Metagenomic Sequencing Research into microbial communities provides a fundamental basis for uncovering hidden interactions within soil, water, intestinal, and other environmental ecosystems. To decode t...Read more -
Epigenetics in Real Time: Unlocking RNA Modifications with Nanopore Direct Sequencing
Epigenetics in Real Time: Unlocking RNA Modifications with Nanopore Direct Sequencing To fully understand cellular function, development, and disease progression, we must look beyond the DNA sequence itself and examine the additional layers of biological information that regulate gene activity:...Read more -
Integrating Non-Targeted Proteomics and mRNA Sequencing for Deeper Biological Insight
Integrating Non-Targeted Proteomics and mRNA Sequencing for Deeper Biological Insight Proteomics is a powerful tool for systematically investigating biological mechanisms. By profiling proteins on a large scale, it provides insight into the biological processes taking place within cells. However,...Read more -
Unlocking the Hidden Language of RNA: Comprehensive Whole Transcriptome Sequencing for Multi-Layer Regulatory Discovery
Unlocking the Hidden Language of RNA: Comprehensive Whole Transcriptome Sequencing for Multi-Layer Regulatory Discovery Beyond Gene Expression: A Complete View of the Transcriptome Modern biological systems are regulated by far more than protein-coding genes alone. While traditional transc...Read more -
Linking Taxonomy, Function, and Metabolism Through Multi-Omics Integration
Linking Taxonomy, Function, and Metabolism Through Multi-Omics Integration The increasing use of multiple omics technologies to study diseases and environments has created a growing need to integrate datasets across different layers of biology. In microbiome studies, this integration is especiall...Read more -
Astral-DIA: Redefining High-Throughput Quantitative Proteomics
Astral-DIA: Redefining High-Throughput Quantitative Proteomics Proteomics focuses on the large-scale profiling of all proteins expressed in cells, tissues and organisms, serving as a critical functional link between genotype and phenotype. Proteins govern nearly all biological processes, includin...Read more -
From Fragment to Full-Length: The Significance of TGS ONT & PacBio Platforms for mRNA Sequencing
From Fragment to Full-Length: The Significance of TGS ONT & PacBio Platforms for mRNA Sequencing For years, short-read sequencing platforms including Illumina and MGI have been widely applied in mRNA sequencing. They feature high base accuracy, sufficient sequencing depth and cost advantages,...Read more -
Beyond the genome: deciphering metabolic diseases through multi-omics integration
Beyond the genome: deciphering metabolic diseases through multi-omics integration Most metabolic diseases, such as Type 2 Diabetes (T2D) and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD, formerly NAFLD), are characterized by a breakdown in systemic homeostasis that no single bi...Read more -
Characterizing Plant Gene Expression in Cell Context: How Spatial Transcriptomics Enables Discovery in Plant Research
Characterizing Plant Gene Expression in Cellular Context: How Spatial Transcriptomics Advances Plant Research Understanding plant development at cellular resolution has long been limited by a key challenge: bulk RNA sequencing captures overall gene expression but loses spatial and cellular contex...Read more -
Wide-Targeted Metabolomics: Bridging Non-Targeted and Targeted for High-Coverage, Reproducible Quantification
Wide-Targeted Metabolomics: Bridging Non-Targeted and Targeted for High-Coverage, Reproducible Quantification Metabolomics serves as a core omics technology in medicine, agricultural research and systems biology. As the downstream readout of genetic, transcriptional and protein regulatory network...Read more -
From Sample to Sequence: Best Practices for Environmental Sample Preparation in Microbiome Research
From Sample to Sequence: Best Practices for Environmental Sample Preparation in Microbiome Research Environmental microbiology has transformed our understanding of microbial ecosystems—from soil and water to the human body. However, in microbiome research best practices, one truth remains cons...Read more -
Spatial transcriptomics: Highlights of S3000 platform
Spatial transcriptomics: Highlights of S3000 platform Spatial transcriptomics is a technique that can highly benefit from the technical developments the modern days keep bringing on. In this aspect, the upgrade from S1000 to S3000 in this platform, brought a series of improvements that make it su...Read more -
Spatial Transcriptomics at BMKGENE: A smooth service procedure with multiple quality control points
Spatial Transcriptomics at BMKGENE: A smooth service procedure with multiple quality control points Mapping the cellular landscape is an ambitious journey. At BMKGENE, we believe that Spatial Transcriptomics shouldn’t come with high-stress logistics. Our BMKMANU S3000 platform delivers indu...Read more
