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Case Study: Construction of the Largest and Most Genetically Diverse Upland Cotton Graph Pan-Genome
Case Study: Construction of the Largest and Most Genetically Diverse Upland Cotton Graph Pan-Genome 2026 Early Breakthrough: The world’s largest and most genetically diverse upland cotton (Gossypium hirsutum) graph pan-genome has been constructed. BMKGENE collaborated in genome sequencing (PacBio...Read more -
Starting on proteomics: What’s mass spectrometry and how can it help unravel the proteome
Starting on proteomics: What’s mass spectrometry and how can it help unravel the proteome Proteomics is an interdisciplinary science that allows the exploration of the proteome from different perspectives: the composition levels of proteins, their structure, their biological activity… Under...Read more -
Ultra-Long Read Sequencing: The Indispensable Tool for T2T-Level High-Quality Genome Assembly
Ultra-Long Read Sequencing: The Indispensable Tool for T2T-Level High-Quality Genome Assembly The Continuous Advancement of Reference Genomes Reference genomes serve as the fundamental backbone for genomics and multi-omics data analysis, and high-quality reference genomes are pivotal for in-dep...Read more -
A Beginner’s Guide to RNA Extraction for High-Quality Transcriptome Sequencing
A Beginner’s Guide to RNA Extraction for High-Quality Transcriptome Sequencing RNA sequencing (RNA-seq) has revolutionized biological research, providing unprecedented insights into the transcriptome. This powerful technology allows scientists to not only quantify gene expression levels but...Read more -
How Advanced hWGS/WES Analysis Supports Precision Oncology Research
How Advanced hWGS/WES Analysis Supports Precision Oncology Research Tumor genomes are uniquely complex. Unlike germline samples, cancer tissues carry somatic mutations, copy number alterations, structural rearrangements, clonal heterogeneity, and distinct mutational signatures resulting from hist...Read more -
Hi-C sequencing for de novo Genome Assembly
Hi-C sequencing for de novo Genome Assembly Sequencing Has Become Essential for de novo Genome Assembly As genome projects expand across ecology, agriculture, conservation, and translational biology, assembling genomes to chromosome-scale contiguity has become a universal benchmark. Yet long-read...Read more -
Proteomic Toolkit: Traditional and MS-Based Methods
Proteomic Toolkit: Traditional and MS-Based Methods Every living cell is a bustling city, and proteins are its essential workers. They build structures, carry messages, and perform all the jobs vital for life, mostly guided by our DNA. To truly grasp how a biological system works—whether it’...Read more -
Single-Cell V.S. Spatial Transcriptomics: A Powerful Duo in Modern Biology
Single-Cell V.S. Spatial Transcriptomics: A Powerful Duo in Modern Biology Transcriptomics has transformed biological research, enabling scientists to study the full set of RNA transcripts in cells and tissues. While traditional bulk RNA sequencing offers a broad overview, it misses critical deta...Read more -
BMKMANU’s Upgraded S3000 Spatial Transcriptomics Technology Makes Its Debut in Plant Research
BMKMANU’s Upgraded S3000 Spatial Transcriptomics Technology Makes ItsDebut in Plant Research On September 30, 2025, a research team led by Dr. Hexin Tan published a landmark study in Nature Communications, titled “Single-nucleus transcriptomics reveal the morphogenesis and artemisinin biosy...Read more -
A Step-By-Step Guide to Prepare Plant Sample for Spatial Transcriptomics Sequencing
The spatial organization of cells plays a vital role in various biological processes, such as plant development and cell differentiation, plant-pathogen interactions and abiotic stress response. Spatial transcriptomics represents a cutting-edge methodology for profiling gene expression within pr...Read more
