Featured Genomic Solutions
Advanced high-throughput technologies delivering superior capture efficiency for clinical and scientific research
Biomarker Technologies (BMKGene)
Leading Global Genomics Service Provider
Biomarker Technologies (BMKGene), founded in 2009, is a leading genomics service provider with over 16 years of continuous innovation in high-throughput sequencing and bioinformatics. Backed by more than 60 national invention patents and 200+ software copyrights, we deliver comprehensive multi-omics solutions—spanning genomics, metagenomics, epigenetics, single-cell omics, transcriptomics, and our proprietary BMKMANU S3000 spatial transcriptome technology—supported by our advanced BMKCloud bioinformatics platform. We have established long-term collaborations with organizations across 84 regions worldwide, providing reliable genomic solutions on a global scale.
Our commitment to quality, efficiency, and scientific rigor has made us a trusted partner for universities, pharmaceutical companies, and biotechnology research centers internationally, enabling breakthrough discoveries in human health, agriculture, and environmental science.
Optimizing Capture Efficiency in Berlin's Biotech Ecosystem
Berlin and the surrounding Brandenburg region represent one of Europe's most dynamic life science and biotechnology clusters. Known as the HealthCapital, Berlin is home to world-renowned research institutes such as the Charité - Universitätsmedizin Berlin, the Max Delbrück Center for Molecular Medicine (MDC), and the Berlin Institute of Health (BIH). In this highly competitive scientific landscape, researchers require advanced molecular tools that offer superior capture efficiency to decode complex biological systems.
Capture efficiency—the ability to successfully target, enrich, and sequence specific genomic regions or RNA molecules from low-input or highly degraded samples—is critical for modern precision medicine. Whether identifying rare oncogenic mutations in liquid biopsies or mapping the spatial architecture of tumor microenvironments, BMKGene's state-of-the-art sequencing pipelines provide the high capture efficiency required to translate raw biological samples into actionable diagnostic and therapeutic insights.
Industrial Trends & Spatial Genomics Advancements
How spatial transcriptomics and automated sequencing are reshaping the global biotechnology landscape
The Rise of Spatial Transcriptomics
Traditional RNA sequencing provides an average gene expression profile across a bulk tissue sample, losing crucial spatial context. The modern genomic industry is rapidly shifting toward single-cell and spatial resolution. BMKGene's proprietary BMKMANU S3000 spatial transcriptome technology allows researchers to map gene expression directly onto tissue sections. This technological leap enables researchers in Berlin to visualize cellular interactions in microenvironments, accelerating discovery in oncology, neurobiology, and developmental immunology.
Automation & High-Throughput Workflows
To meet the demands of large-scale clinical trials and population-scale genomics, automation in library preparation is no longer optional. Manual library prep introduces batch variations and potential sample loss, which drastically degrades capture efficiency. Automated platforms like the Brilliant Lab 1000 (BL1000) streamline workflows, ensuring consistent yield, high multiplexing capabilities, and rapid turnaround times essential for modern biotechnology hubs.
Multi-Omics Integration
The integration of genomics, transcriptomics, epigenomics, and proteomics offers a holistic view of biological systems. Leveraging advanced bioinformatics platforms like BMKCloud, researchers can process massive datasets simultaneously. This multi-omics approach is crucial for discovering complex biomarkers and understanding multifactorial diseases, positioning Berlin-based laboratories at the cutting edge of personalized medicine.
Our Advanced Analytical Platforms
Equipped with industry-leading sequencing and molecular analysis technologies
Multi-Level Sequencing Platforms
PacBio platforms: Sequel II, Sequel, RSII
Nanopore platforms: PromethION P48, GridION X5 MinION
10X Genomics: 10X ChromiumX, 10X Chromium Controller
Illumina platforms: NovaSeq
BGI-sequencing platforms: DNBSEQ-G400, DNBSEQ-T7
Bionano Irys system
Waters XEVO G2-XS QTOF
QTRAP 6500+
Professional Automatic Laboratory
Spanning over 20,000 square feet of state-of-the-art laboratory space.
Equipped with advanced biomolecular laboratory instruments.
Standardized workflows for sample extraction, library construction, clean rooms, and sequencing labs under strict SOPs to guarantee high capture efficiency.
Reliable Bioinformatic Analysis
Self-developed BMKCloud platform tailored for high-performance computing.
CPUs with 41,104 memory and 3 PB total storage capacity.
4,260 computing cores with peak computing power exceeding 121,708.8 Gflop per second, enabling rapid data processing and deep biological insights.
Localized Applications in Berlin & Germany
Bridging advanced genomic technologies with real-world clinical, agricultural, and environmental research
Oncology & Immunotherapy at Charité
Berlin's clinical research centers heavily focus on targeted oncology and personalized immunotherapy. By utilizing whole transcriptome and exosomal RNA sequencing, clinical researchers can discover novel biomarkers for cancer progression. High capture efficiency ensures that low-abundance exosomal RNAs are successfully captured, giving clinicians a detailed view of the tumor microenvironment to guide treatment plans.
Neuroscience & Brain Mapping at MDC
The Max Delbrück Center (MDC) in Berlin-Buch is renowned for its neural stem cell and brain development research. Using spatial transcriptomics (BMKMANU S3000) and long-read sequencing (Nanopore/PacBio), scientists can map splicing isoforms and gene expression patterns in complex brain tissues, preserving spatial context to better understand neurodegenerative disorders like Alzheimer's and Parkinson's.
Agricultural & Environmental Metagenomics
Brandenburg's agricultural institutes apply bacterial and fungal whole-genome re-sequencing to study soil microbiomes, crop resistance, and plant-pathogen interactions. Maximizing capture efficiency in metagenomic samples allows for the detection of rare microbial species that play critical roles in crop health, driving sustainable agriculture practices across Germany.
Fully Automated Platform: Brilliant Lab 1000
Biomarker Technologies (BMKGene) and PerkinElmer have jointly built a fully automated experimental production line, called Brilliant Lab 1000 (BL1000), which is applied to high-throughput NGS library construction services.
BMKGene strives to greatly improve the entire line of sequencing products in terms of product types, production line throughput, delivery quality, and cycle time, to provide customers with better sequencing services.
Enterprise Qualifications & Academic Collaborations
Demonstrated excellence and compliance with international standards in genomics and biotechnology
Certification on Nanopore-based service provider
Joint Laboratory of Biomarker Technologies Co., LTD, PacBio, and Gene Company Ltd.
National Academician Research Workstation
Joint Laboratory between Biomarker Technologies Co., LTD and PerkinElmer Inc.
Teaching Practice Base of Huazhong Agricultural University
Post-doctoral Research Workstation
Joint Laboratory of BioCloud Computing with Huazhong Agricultural University
National High and New Technology Enterprise Qualification
ISO9001 Quality Certification
ISO14001 Environmental Certification
OHSAS 18001 Occupational Health & Safety
Patent: Bioinformatics Task Monitoring System
Patent: BSA-based Biomolecular Marker Discovery
Patent: High-Density Linkage Map Construction
Patent: Plant Genome DNA Extraction Method
Software Copyright: Hi-C Based Genome Assembly
Software Copyright: Species Database Construction
Patent: BMKCloud LncRNA Sequencing Analysis
Patent: Genome De Novo Assembly Method
Patent: High-Throughput Data Analysis System
Patent: RRS Library Construction
Software Copyright: Hi-C Facilitated Genome Assembly
Patent: BMKCloud Platform
Patent: Hi-C Library Construction Method
Patent: Non-Reference Genome RNA-Seq Analysis
Patent: SLAF-Seq Related Technique
Software Copyright: Microbiome Analysis Pipeline
Our Complete Product Portfolio
Reliable and comprehensive multi-omics solutions tailored for scientific breakthrough
Whole Transcriptome Sequencing - Illumina
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Bacterial and Fungal Whole Genome Re-Sequencing
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DNA/RNA Sequencing – Nanopore Sequencer
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Human Whole Genome Sequencing
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TGuide Smart Magnetic Tissue DNA Kit
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Exosomal mRNA/LncRNA/CircRNA Sequencing - Illumina
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PacBio 2+3 Full-Length mRNA Solution
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mRNA (Reference) Analysis
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For inquiries about our sequencing products, spatial transcriptome options, or custom pricelists, please contact us. We will be in touch within 24 hours.
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