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Kayayyaki

Binciken Ƙungiya mai Faɗi

Nazarin ƙungiyar genome-wide (GWAS) yana nufin gano bambance-bambancen kwayoyin halitta (genotype) waɗanda ke da alaƙa da takamaiman halaye (phenotype).Nazarin GWAS yana bincika alamomin kwayoyin halitta sun haye dukkanin kwayoyin halittar mutane masu yawa kuma yana tsinkayar ƙungiyoyin genotype-phenotype ta ƙididdigar ƙididdiga a matakin yawan jama'a.An yi amfani da shi sosai a cikin bincike kan cututtukan ɗan adam da aikin haƙar ma'adinan kwayoyin halitta akan hadaddun halaye na dabbobi ko tsirrai.


Cikakkun Sabis

Sakamakon Demo

Fitar Bugawa

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1. Amfanin Sabis

Yawan Ayyukan Ayyuka: Tun lokacin da aka kafa shi a cikin 2009, BMKGENE ya kammala ɗaruruwan ayyukan jinsuna a cikin binciken GWAS na yawan jama'a, ya taimaka wa masu bincike don buga labarai fiye da 100, kuma tasirin tasirin tasirin ya kai 500.
● Kwararrun manazarta.
● gajeren zagayowar bincike.
● Ma'adinan bayanai daidai.

2. Bayanin Sabis

Nau'in

Girman Yawan Jama'a

Dabarun tsarawa da zurfi

SLF-GWAS Misalin lamba ≥200 Girman kwayoyin halitta <400M, tare da ref-genome, WGS ana ba da shawarar

Girman Genome ≤ 1G, 100K Tags da 10X

1G ≤ Girman Genome ≤ 2G, 200K Tags da 10X

Girman Genome> 2G, Tags 300K da 10X

WGS-GWAS

Misalin lamba ≥200

10X ga kowane samfurin

3. Zaɓin kayan aiki

动物1
动物2
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Daban-daban iri, kasaftawa, landbles / Genebanks / hade da iyalai / albarkatun daji

Daban-daban iri-iri, nau'ikan nau'ikan, nau'ikan ƙasa

Half-sib iyali/cikakkiyar iyali / albarkatun daji

4. Binciken Halittu

● Binciken ƙungiyoyi masu fa'ida
● Bincike da nunawa na SNP masu mahimmanci
● Bayanin aiki na jinsin ɗan takara

5. Gudun Aikin Sabis

Misalin QC

Gwajin ƙira

samfurin bayarwa

Samfurin bayarwa

Gwajin matukin jirgi

RNA cirewa

Shirye-shiryen Laburare

Gina ɗakin karatu

Jeri

Jeri

Binciken bayanai

Binciken bayanai

Bayan Sabis na siyarwa

Bayan-sayar da sabis


  • Na baya:
  • Na gaba:

  • a.Phenotype QC

    Histogram na rarraba mita

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    Ƙididdiga na Phenotype

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    b.Binciken ƙungiyoyi (Model: GEMMA, FaST-LMM, EMMAX)

    Tsarin QQ

    hoto 11

    Manhattan Plot

    Ammonia_emmax_manhattan_00

    Shekara

    Jarida

    IF

    Take

    2022

    NC

    17.69

    Tsarin genomic na giga-chromosomes da giga-genome na itacen peony Paeonia ostii

    2015

    NP

    7.43

    Sawun gida yana kafa yankuna masu mahimmancin aikin gona a cikin waken soya

    2018

    MP

    9.32

    Gabaɗaya-genome mai kama da tarin nau'ikan nau'ikan fyade a duniya yana bayyana tushen asalin halittar halittarsu

    2022

    HR

    7.29

    Binciken haɗin gwiwar genome-fadi yana ba da fahimtar kwayoyin halitta game da bambancin yanayin girman irin kankana

    samun zance

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