ʻIkepili ʻAhahui Genome-wide
1.Service Pono
● Nui nā hihia papahana: mai kona hoʻokumu ʻia ʻana i ka makahiki 2009, ua hoʻopau ʻo BMKGENE i nā haneli o nā ʻano papahana i ka noiʻi ʻana o ka heluna kanaka GWAS, kōkua i nā mea noiʻi e paʻi i nā ʻatikala ma mua o 100, a ua hiki ke kumu kumulative hopena i 500.
● Nā kānaka kālailai ʻoihana.
● Pōkole kālailai pōʻaiapuni.
● ʻImi ʻikepili pololei.
2. Nā kikoʻī lawelawe
| ʻAno | Ka heluna kanaka | Hoʻolālā kaʻina a me ka hohonu |
| SLAF-GWAS | Helu laʻana ≥200 | ʻO ka nui genome <400M, me ka ref-genome, ʻōlelo ʻia ʻo WGS |
| Ka nui genome ≤ 1G, 100K Tags a me 10X | ||
| 1G ≤ Nui genome ≤ 2G, 200K mau huaʻōlelo a me 10X | ||
| Ka nui Genome > 2G, 300K Tags a me 10X | ||
| WGS-GWAS | Helu laʻana ≥200 | 10X no kēlā me kēia hāpana |
3. Koho Mea
Nā ʻano like ʻole, subspecies, landraces/genebanks/mixed family/wild resources
ʻO nā ʻano like ʻole, subspecies, landraces
ʻOhana hapa-sib/ʻohana-sib piha/ ʻohana ʻāhiu
4. ʻIkepili Bioinformation
● Kānāwai hui pūʻokoʻa genome
● Ka nānā ʻana a me ka nānā ʻana i ka SNP nui
● Palapala kikoo o ka gene moho
5. Hana Hana Hana
Hoʻolālā hoʻokolohua
Hāʻawi laʻana
RNA unuhi
Kūkulu hale waihona puke
Ke kaʻina ʻana
ʻIkepili ʻikepili
Nā lawelawe ma hope o ke kūʻai aku
a.Phenotype QC
Histogram māhele alapine
ʻIkepili Phenotype
b.Ka nānā 'ana i ka hui (Mode: GEMMA, FaST-LMM, EMMAX)
Kūlana QQ
ʻĀpana Manhattan
| Makahiki | Nupepa | IF | Poʻo inoa |
| 2022 | NC | 17.69 | Ke kumu genomic o ka giga-chromosomes a me ka giga-genome o ka laau peony Paeonia ostii |
| 2015 | NP | 7.43 | Hoʻokumu nā kapuaʻi home i nā wahi genomic koʻikoʻi agronomic i ka soybeans |
| 2018 | MP | 9.32 | ʻO ka hoʻihoʻi ʻana o ka genome holoʻokoʻa o kahi hōʻiliʻili honua āpau o ka komo ʻana i ka rapeseed e hōʻike ana i ke kumu genetic o kā lākou ecotype divergence |
| 2022 | HR | 7.29 | Hāʻawi ka ʻimi ʻana i ka hui ʻana o Genome-wide i nā ʻike molekala i ke ʻano kūlohelohe o ka nui o ka hua melon |
