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Kev kawm txog Proteomics
Proteomics tsom mus rau cov protein—cov neeg ua haujlwm ntawm lub neej ua ub ua no uas ua lub luag haujlwm tseem ceeb hauv kev tswj hwm kev sau ntawv ntawm lub cev. Nws tshuaj xyuas cov khoom sib xyaw, cov qib kev qhia tawm, thiab cov xwm txheej hloov pauv ntawm txhua cov protein hloov pauv hauv cov ntaub so ntswg lossis cov hlwb, hais txog qhov cuam tshuam tseem ceeb ntawm cov protein ntau ntawm cov txheej txheem hauv lub neej. Siv dav hauv kev kho mob, kev ua liaj ua teb, thiab kev yug tsiaj. Cov Proteomics zoo siv cov thev naus laus zis txheeb xyuas cov protein HPLC-MS/MS los txheeb xyuas cov qauv suav nrog cov gel strips, IP, thiab CO-IP/Pull down samples. Quantitative Proteomics ua tiav qhov tseeb ntawm kev ntsuas thiab kev txheeb xyuas ntawm txhua cov protein uas qhia los ntawm genome lossis hauv ib qho system sib xyaw ua ke. Cov thev naus laus zis proteomics tam sim no feem ntau yog muab faib ua cov cim (TMT) thiab cov cim tsis muaj (Label Free, DIA, PRM). BMKGENE muab ntau lub platform thiab ntau cov thev naus laus zis proteomics kev daws teeb meem.
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Kev Tshawb Fawb Txog Metabolomics
Kev kawm txog kev hloov pauv ntawm cov metabolism, uas yog ib qho kev kawm txuas ntxiv ntawm genomics, feem ntau yog tsom mus rau cov tshuaj me me uas muaj qhov hnyav molecular tsawg dua 1500 Da. Nws ua rau cov metabolites muaj peev xwm cuam tshuam cov kab mob cov lus teb rau cov kev hloov pauv sab nraud thiab kev hloov pauv ntawm lub cev/kev mob nkeeg tau zoo dua. Kev hloov pauv ntawm cov metabolism uas ua rau muaj kev hloov pauv ntawm cov noob caj noob ces kuj yog ib qho kev tshawb fawb tshiab, muab ib qho kev xav tshiab rau kev tshawb fawb.
BMKGENE muab ntau yam kev pabcuam metabolomics, suav nrog cov metabolomics uas tsis yog lub hom phiaj, cov metabolomics uas tau tsom mus rau ntau yam, thiab cov metabolomics uas tau tsom mus rau lub hom phiaj. Siv cov kua chromatography-mass spectrometry (LC-MS) lossis roj chromatography-mass spectrometry (GC-MS), cov kev hloov pauv dynamic hauv feem ntau cov metabolites me me hauv cov kab mob ua ntej thiab tom qab kev txhawb nqa sab nraud tuaj yeem pom. Lub hauv paus ntawm cov kev pabcuam no yog nyob rau hauv kev txheeb xyuas cov metabolites nrog qhov sib txawv tseem ceeb ntawm cov pab pawg sim thiab cov pab pawg tswj thiab tshawb nrhiav ntxiv lawv txoj kev sib raug zoo nrog kev hloov pauv physiological / pathological thiab cov txheej txheem hauv qab.
