Discover our premier high-throughput sequencing options designed to maximize your on-target rate efficiency and yield precise biological insights.
In the realm of Next-Generation Sequencing (NGS) and targeted enrichment, the on-target rate is a vital performance metric. It defines the percentage of sequenced reads that align successfully to the target regions of interest (such as exons in whole-exome sequencing or specific loci in custom gene panels) relative to the total reads generated. A high on-target rate indicates that the sequencing run was highly specific, yielding maximum data for the targeted regions while minimizing wasted reads on off-target genomic noise. For research labs and clinical institutions, optimizing this rate directly translates to lower sequencing depths required per sample, thereby significantly reducing overall operational costs.
Brazil represents the largest biotechnology and life sciences market in Latin America. With a robust academic network including institutions like the University of São Paulo (USP), State University of Campinas (UNICAMP), and the Oswaldo Cruz Foundation (Fiocruz), the demand for genomic sequencing has grown exponentially. In recent years, Brazil’s industrial sectors—ranging from agribusiness to clinical diagnostics—have increasingly integrated genomic data into their core workflows. However, local researchers face unique challenges, such as high import taxes on reagents and long transit times for international shipments. Consequently, obtaining competitive on-target rate quotes from a reliable global partner like BMKGene is essential for local laboratories to optimize their budgets and achieve international sequencing standards.
Brazil's massive agricultural sector relies on genomic selection to breed climate-resilient crops and high-yield livestock.
Increasing demand for custom gene panels to diagnose rare diseases and optimize oncological treatments in diverse populations.
Unlocking the genetic secrets of the Amazon rainforest through metagenomics and target-enrichment sequencing.
Targeted sequencing applications in Brazil are highly localized to address the country's unique ecological, economic, and medical demands:
Biomarker Technologies (BMKGene), founded in 2009, is a leading genomics service provider with over 16 years of continuous innovation in high-throughput sequencing and bioinformatics. Backed by more than 60 national invention patents and 200+ software copyrights, we deliver comprehensive multi-omics solutions—spanning genomics, metagenomics, epigenetics, single-cell omics, transcriptomics, and our proprietary BMKMANU S3000 spatial transcriptome technology—supported by our advanced BMKCloud bioinformatics platform. We have established long-term collaborations with organizations across 84 regions worldwide, providing reliable genomic solutions on a global scale.
BMKGene operates a multi-level high-throughput sequencing laboratory equipped with the industry's leading platforms, ensuring maximum flexibility and data accuracy for every project scale.
PacBio platforms: Sequel II, Sequel, RSII
Nanopore platforms: PromethION P48, GridION X5, MinION
10X Genomics: 10X ChromiumX, 10X Chromium Controller
Illumina platforms: NovaSeq
BGI-sequencing platforms: DNBSEQ-G400, DNBSEQ-T7
Bionano Irys system, Waters XEVO G2-XS QTOF, QTRAP 6500+
Advanced biomolecular laboratory instruments.
Standard labs of sample extraction, library construction, clean rooms, and sequencing labs.
Standard procedures from sample extraction to sequencing under strict SOPs to maintain optimal on-target rates.
Self-developed BMKCloud platform.
CPUs with 41,104 memory and 3 PB total storage.
4,260 computing cores with peak computing power over 121,708.8 Gflop per second, enabling rapid alignment and on-target rate calculations.
Biomarker Technologies (BMKGene) and PerkinElmer have jointly built a fully automated experimental production line, called Brilliant Lab 1000 (BL1000), which is applied to the high-throughput NGS library construction service.
BMKGENE strives to greatly improve the entire line of sequencing products in terms of product types, production line throughput, delivery quality, and cycle time, to provide customers with better sequencing services. By utilizing automated liquid handling, we minimize human error, ensuring highly reproducible library preparation and consistently high on-target rates for target enrichment assays.
A visual journey inside our high-throughput sequencing facilities and cleanrooms, where strict standard operating procedures guarantee the integrity of your biological samples.









Browse our full range of sequencing services, optimized for high on-target rates and precise genomic assembly.