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Proteomics
Proteomics focuses on proteins—the executors of life activities that play a crucial role in organismal transcription regulation. It analyzes the composition, expression levels, and modification states of all dynamically changing proteins in tissues or cells, addressing the significant impact of proteome abundance dynamics on various life processes. Widely applied in medicine, agriculture, and animal husbandry. Qualitative Proteomics utilizes HPLC-MS/MS protein identification technology to identify samples including gel strips, IP, and CO-IP/Pull down samples. Quantitative Proteomics achieves accurate quantification and identification of all proteins expressed by a genome or in a complex mixed system. Current quantitative proteomics technologies are mainly categorized into labeled (TMT) and label-free (Label Free, DIA, PRM) approaches. BMKGENE provides multi-platform and multi-technology proteomics solutions.
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Metabolomics
Metabolomics, a downstream discipline of genomics, mainly targets small-molecule substances with a molecular weight of less than 1500 Da. It enables metabolites to reflect organisms’ responses to external stimuli and physiological/pathological changes more sensitively. Genetic variations-induced metabolite level changes are also within its research scope, providing a novel research perspective.
BMKGENE offers a full range of metabolomics services, including non-targeted metabolomics, widely targeted metabolomics, and targeted metabolomics. Using liquid chromatography-mass spectrometry (LC-MS) or gas chromatography-mass spectrometry (GC-MS), the dynamic changes in most small-molecule metabolites in organisms before and after external stimulation can be detected. The core of these services lies in identifying metabolites with significant differences between experimental and control groups and further exploring their correlation with physiological/pathological changes and the underlying mechanisms.
