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Genome-wide Association Analysis

Genome-wide association study (GWAS) ine chinangwa chekutsvaga mazita akasiyana-siyana (genotype) ane hukama nemaitiro chaiwo (phenotype).Chidzidzo cheGWAS chinoongorora ma genetic markers anoyambuka genome yenhamba huru yevanhu uye inofanotaura genotype-phenotype masangano kuburikidza nenhamba yekuongorora pahuwandu hwevanhu.Yakashandiswa zvakanyanya mukutsvagisa zvirwere zvevanhu uye kushanda kwemajini kumigodhi pahunhu hwakaoma hwemhuka kana zvirimwa.


Service Details

Demo Result

Featured Publication

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1.Service Advantages

● Yakawanda Project Cases: kubvira payakavambwa muna 2009, BMKGENE yapedza mazana emapurojekiti ezvipenyu mukutsvagisa kwehuwandu hweGWAS, yakabatsira vaongorori kutsikisa zvinopfuura zvinyorwa zve100, uye kuwedzera kwemhedzisiro yakasvika mazana mashanu.
● Nyanzvi dzekuongorora.
● Nguva pfupi yekuongorora.
● Kuchera data kwakarurama.

2. Zvinyorwa zveSevhisi

Type

Population Scale

Sequencing strategy nekudzika

SLAF-GWAS Nhamba yemuenzaniso ≥200 Genome size <400M, ine ref-genome, WGS inokurudzirwa

Genome size ≤ 1G, 100K Tags uye 10X

1G ≤ Saizi yeGenome ≤ 2G, 200K Tags uye 10X

Genome size> 2G, 300K Tags uye 10X

WGS-GWAS

Nhamba yemuenzaniso ≥200

10X yemuenzaniso wega wega

3. Kusarudzwa kwezvinhu

动物1
动物2
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Mhando dzakasiyana, subspecies, landraces / genebanks / mhuri dzakasanganiswa / zviwanikwa zvemusango

Mhando dzakasiyana, subspecies, landraces

Half-sib family/full-sib family/wild resources

4. Bioinformation Analysis

● Genome-wide association analysis
● Kuongorora uye kuongororwa kweSNP inokosha
● Kushanda annotation yejini yemumiriri

5. Kuyerera Kwebasa Rebasa

Muenzaniso QC

Kuedza kugadzira

sampuli yekuendesa

Muenzaniso wekutumira

Pilot experiment

RNA kubviswa

Kugadzirira Raibhurari

Kuvakwa kweraibhurari

Sequencing

Sequencing

Data analysis

Data analysis

Mushure mekutengesa Services

Mushure mekutengesa masevhisi


  • Zvakapfuura:
  • Zvinotevera:

  • a.Phenotype QC

    Frequency distribution histogram

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    Phenotype nhamba

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    b.Ongororo yemubatanidzwa (Muenzaniso: GEMMA, FaST-LMM, EMMAX)

    Nhoroondo yeQQ

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    Manhattan Plot

    Ammonia_emmax_manhattan_00

    Gore

    Journal

    IF

    Title

    2022

    NC

    17.69

    Genomic hwaro hwegiga-chromosomes uye giga-genome yemuti peony Paeonia ostii

    2015

    NP

    7.43

    Domestication footprints anchor genomic regions of agronomic value musoya beans

    2018

    MP

    9.32

    Yese-genome requencing yepasi rose muunganidzwa wezvakabatwa chibharo zvinoburitsa genetic hwaro hwekusiyana kwavo ecotype.

    2022

    HR

    7.29

    Kuongororwa kweGenome-wide association kunopa ma molecular nzwisiso mukusiyana kwechisikigo kwekukura kwembeu yemavito

    kuwana quote

    Nyora meseji yako pano uye titumire kwatiri

    Tumira meseji yako kwatiri: