Genome-jakejado Association Analysis
1.Service Anfani
● Awọn ọran Iṣeduro Ọpọlọpọ: lati igba idasile rẹ ni ọdun 2009, BMKGENE ti pari awọn ọgọọgọrun awọn iṣẹ akanṣe ninu awọn iwadii olugbe GWAS, ṣe iranlọwọ fun awọn oniwadi lati ṣe atẹjade diẹ sii ju awọn nkan 100, ati pe ipa ipa akopọ ti de 500.
● Awọn atunnkanka ọjọgbọn.
● Ayika itupalẹ kukuru.
● Iwakusa data deede.
2. Iṣẹ pato
| Iru | Iwọn Olugbe | Ilana titele ati ijinle |
| SLAF-GWAS | Nọmba apẹẹrẹ ≥200 | Iwọn genome <400M, pẹlu ref-genome, WGS ni iṣeduro |
| Iwọn jiini ≤ 1G, Awọn afi 100K ati 10X | ||
| 1G ≤ Iwọn Jiini ≤ 2G, Awọn afi 200K ati 10X | ||
| Iwọn Jiini> 2G, Awọn afi 300K ati 10X | ||
| WGS-GWAS | Nọmba apẹẹrẹ ≥200 | 10X fun ayẹwo kọọkan |
3. Aṣayan ohun elo
Awọn oriṣiriṣi oriṣiriṣi, awọn ẹya-ara, awọn ilẹ-ilẹ / awọn banki apilẹṣẹ / awọn idile ti o dapọ / awọn orisun igbẹ
Awọn oriṣiriṣi oriṣiriṣi, awọn ẹya-ara, awọn ilẹ-ilẹ
Idaji-sib ebi / full-sib ebi / egan oro
4. Bioinformation Analysis
● Atunyẹwo ẹgbẹ-ara-jakejado
● Onínọmbà ati ayẹwo ti SNP pataki
● Apejuwe iṣẹ-ṣiṣe ti Jiini oludije
5. Sisan Iṣẹ Iṣẹ
Apẹrẹ adanwo
Ifijiṣẹ apẹẹrẹ
RNA isediwon
Ikole ìkàwé
Titele
Itupalẹ data
Lẹhin-tita awọn iṣẹ
a.Phenotype QC
Igbohunsafẹfẹ pinpin histogram
Awọn iṣiro Phenotype
b.Itupalẹ ẹgbẹ (Awoṣe: GEMMA, FaST-LMM, EMMAX)
Idite QQ
Manhattan Idite
| Odun | Iwe akosile | IF | Akọle |
| 2022 | NC | 17.69 | Ipilẹ jiini ti awọn giga-chromosomes ati giga-genome ti igi peony Paeonia ostii |
| Ọdun 2015 | NP | 7.43 | Awọn ifẹsẹtẹ inu ile dakọ awọn agbegbe genomic ti pataki agronomic ni awọn ẹwa soy |
| 2018 | MP | 9.32 | Odidi-jinomii ti o tẹle ti ikojọpọ jakejado agbaye ti awọn ifipabanilopo irugbin ṣe afihan ipilẹ jiini ti iyatọ ecotype wọn |
| 2022 | HR | 7.29 | Ṣiṣayẹwo ẹgbẹ jakejado-genome n pese awọn oye molikula sinu iyatọ adayeba ti iwọn irugbin elegede |
