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Ama-Proteomics
I-Proteomics igxile kumaprotheni—abaphathi bemisebenzi yokuphila edlala indima ebalulekile ekulawulweni kokubhalwa kwezinto eziphilayo. Ihlaziya ukwakheka, amazinga okuvezwa, kanye nezimo zokuguqulwa kwawo wonke amaprotheni ashintsha ngokuguquguqukayo ezicutshini noma emaseli, ibhekana nomthelela obalulekile we-proteome voluminous dynamics ezinqubweni ezahlukene zokuphila. Isetshenziswa kabanzi kwezokwelapha, kwezolimo, kanye nasekufuyweni kwezilwane. I-Qualitative Proteomics isebenzisa ubuchwepheshe bokuhlonza amaprotheni e-HPLC-MS/MS ukuhlonza amasampula afaka phakathi ama-gel strips, i-IP, kanye namasampula e-CO-IP/Pull down. I-Quantitative Proteomics ifinyelela ukulinganiswa okunembile kanye nokuhlonza wonke amaprotheni avezwa yi-genome noma ohlelweni oluxubile oluyinkimbinkimbi. Ubuchwepheshe bamanje be-quantitative proteomics buhlukaniswe kakhulu ngezindlela ezibhalwe ngamalebula (TMT) kanye nezingabhalwe ngamalebula (Azinawo Amalebula, i-DIA, i-PRM). I-BMKGENE inikeza izixazululo ze-proteomics ezinamapulatifomu amaningi kanye nobuchwepheshe obuningi.
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I-Metabolomics
I-Metabolomics, isifunda esingezansi se-genomics, ihlose kakhulu izinto ezincane zama-molecule ezinesisindo sama-molecule esingaphansi kuka-1500 Da. Ivumela ama-metabolites ukuthi abonise izimpendulo zezinto eziphilayo ezintweni zangaphandle kanye nezinguquko zomzimba/ze-pathological ngendlela ebucayi kakhulu. Ukushintsha kwezakhi zofuzo-ushintsho lwezinga le-metabolite olubangelwa ukushintsha kwezakhi zofuzo nakho kungaphakathi kobubanzi bayo bocwaningo, okunikeza umbono omusha wocwaningo.
I-BMKGENE inikeza uhla oluphelele lwezinsizakalo ze-metabolomics, kufaka phakathi i-metabolomics engahlosiwe, i-metabolomics ehlosiwe kakhulu, kanye ne-metabolomics ehlosiwe. Ukusebenzisa i-liquid chromatography-mass spectrometry (LC-MS) noma i-gas chromatography-mass spectrometry (GC-MS), izinguquko eziguquguqukayo kuma-metabolites amaningi amancane ezintweni eziphilayo ngaphambi nangemva kokukhuthazwa kwangaphandle kungatholakala. Ingqikithi yalezi zinsizakalo itholakala ekuboneni ama-metabolites anomehluko omkhulu phakathi kwamaqembu okuhlola nawokulawula kanye nokuhlola kabanzi ukuhlobana kwawo nezinguquko zomzimba/ze-pathological kanye nezindlela eziyisisekelo.
