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I-Evolutionary Genetics
Inani labantu kunye neqonga lokuhlalutya imfuzo lisekwe kwisiseko samava amakhulu aqokelelwe kwiqela le-BMK R&D iminyaka.Sisixhobo esisebenziseka lula ngakumbi kubaphandi abangabalulekanga kwi-bioinformatics.Eli qonga livumela uhlalutyo olusisiseko olunxulumene nofuzo olusisiseko olubandakanya ukwakhiwa komthi we-phylogenetic, uhlalutyo lwe-disequilibrium yokunxibelelana, uvavanyo lokwahluka kwemfuza, uhlalutyo olukhethiweyo lokutshayela, uhlalutyo lokuzalana, i-PCA, uhlalutyo lwesakhiwo sabemi, njl.
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malunga ne-RNA
I-RNA yeSetyhula (i-circRNA) luhlobo lwe-RNA engeyiyo ikhowudi, esandul 'ukufumanisa ukuba idlala indima ebalulekileyo kuthungelwano olulawulayo olubandakanyekayo ekuphuhliseni, ukuchasana nokusingqongileyo, njl njl. Ukwahlukileyo kwi-molecule ye-RNA ecacileyo, umzekelo, i-mRNA, i-lncRNA, i-3 kunye ne-5 iziphelo ze-circRNA zidityaniswe kunye zenze isakhelo sesetyhula, esibasindisa ekugayweni kwe-exonuclease kwaye zizinzile ngakumbi kune-RNA eninzi.I-CircRNA ifunyenwe inemisebenzi eyahlukeneyo yokulawula ukubonakaliswa kofuzo.I-CircRNA inokusebenza njenge-ceRNA, ebopha i-miRNA ngokhuphiswano, eyaziwa ngokuba yi-miRNA sponge.Iqonga lokuhlalutya lolandelelwano lwe-CircRNA lixhobisa ubume be-circRNA kunye nohlalutyo lwentetho, ukuqikelela okujoliswe kuko kunye nohlalutyo oludibeneyo kunye nezinye iintlobo ze-molecule ze-RNA.
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BSA
Iqonga le-Bulked Segregant Analysis iquka uhlalutyo olusemgangathweni lwenqanaba elinye kunye nohlalutyo oluphambili kunye nokumisela ipharamitha elungiselelwe.I-BSA bubuchule obusetyenziselwa ukuchonga ngokukhawuleza iimpawu zofuzo ezinxulumene nephenotype.Umsebenzi ongundoqo we-BSA uqulathe: 1. ukukhetha amaqela amabini abantu abaneephenotypes ezichasene kakhulu;2. ukudibanisa i-DNA, i-RNA okanye i-SLAF-seq(Iphuhliswe yi-Biomarker) yabo bonke abantu ukuze benze isambuku esibini se-DNA;3. ukuchonga ulandelelwano olwahlukileyo ngokuchasene ne-reference genome okanye phakathi, 4. ukuqikelela umviwa onxibelelene nemimandla nge-ED kunye ne-SNP-index algorithm;5. Ucazululo olusebenzayo kunye nophuculo kwiijini kwimimandla yabaviwa, njl. njl. Ukumbiwa kwedatha okuqhubele phambili ngakumbi kubandakanywa nokuhlolwa kophawu lwemfuza kunye noyilo lweprimer kukwakhona.
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I-Amplicon (16S/18S/ITS)
I-Amplicon (16S / 18S / ITS) iqonga liphuhliswa kunye neminyaka yamava kuhlalutyo lweprojekthi ye-microbial diversity, equlethe uhlalutyo olusisiseko olusemgangathweni kunye nohlalutyo lomntu: uhlalutyo olusisiseko lubandakanya umxholo wohlalutyo oluqhelekileyo lophando lwe-microbial lwangoku, umxholo wokuhlalutya ucebile kwaye ubanzi, kunye neziphumo zohlalutyo zinikezelwe ngohlobo lweengxelo zeprojekthi;Umxholo wohlalutyo lobuqu uhlukile.Iisampulu zinokukhethwa kwaye iiparamitha zinokumiselwa ngokuguquguqukayo ngokwengxelo yohlalutyo olusisiseko kunye nenjongo yophando, ukufezekisa iimfuno zomntu.Inkqubo yokusebenza yeWindows, ilula kwaye iyakhawuleza.
