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Evolutionary Genetics
Pulatifomu yowunikira anthu komanso kusintha kwa majini imakhazikitsidwa potengera zomwe zachitika mu gulu la BMK R&D kwazaka zambiri.Ndi chida chosavuta kugwiritsa ntchito makamaka kwa ofufuza omwe sachita zazikulu mu bioinformatics.Pulatifomuyi imathandizira kusanthula koyambira kokhudzana ndi kusinthika kwa ma genetics kuphatikiza kupanga mitengo ya phylogenetic, kusanthula kwa kulumikizana, kuwunika kwamitundu yosiyanasiyana, kusanthula kosankha, kusanthula ubale, PCA, kusanthula kamangidwe ka anthu, ndi zina zambiri.
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kuzungulira-RNA
RNA yozungulira (circRNA) ndi mtundu wa RNA yosalemba, yomwe posachedwapa imapezeka kuti ikugwira ntchito yofunika kwambiri pamagulu olamulira omwe akukhudzidwa ndi chitukuko, kukana zachilengedwe, ndi zina zotero. Zosiyana ndi mamolekyu a RNA, mwachitsanzo mRNA, lncRNA, 3' ndi 5'. malekezero a circRNA amalumikizidwa palimodzi kuti apange mawonekedwe ozungulira, omwe amawapulumutsa ku chimbudzi cha exonuclease ndipo amakhala okhazikika kuposa ma RNA ambiri.CircRNA yapezeka kuti ili ndi ntchito zosiyanasiyana pakuwongolera ma jini.CircRNA imatha kuchita ngati ceRNA, yomwe imamanga miRNA mopikisana, yotchedwa miRNA siponji.CircRNA sequencing analysis platform imapatsa mphamvu circRNA kapangidwe ndi kusanthula mawu, kulosera chandamale ndi kusanthula pamodzi ndi mitundu ina ya mamolekyu a RNA.
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BSA
Pulatifomu ya Bulked Segregant Analysis ili ndi gawo limodzi lowunikira komanso kusanthula kwapamwamba kokhala ndi makonda okhazikika.BSA ndi njira yomwe imagwiritsidwa ntchito pozindikira mwachangu zolembera zamtundu wa phenotype.Kuyenda kwakukulu kwa BSA kuli ndi: 1. kusankha magulu awiri a anthu omwe ali ndi ma phenotypes otsutsana kwambiri;2. kuphatikiza DNA, RNA kapena SLAF-seq(Yopangidwa ndi Biomarker) ya anthu onse kuti apange DNA yambiri;3. Kuzindikiritsa kutsatizana kosiyana ndi ma genome kapena pakati, 4. kulosera madera olumikizidwa ndi ED ndi SNP-index algorithm;5. Kusanthula kogwira ntchito ndi kulemeretsa ma jini m'magawo osankhidwa, ndi zina zambiri. Migodi yotsogola kwambiri mu data kuphatikiza kuwunika kwa ma genetic marker ndi mapangidwe oyambira amapezekanso.
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Amplicon (16S/18S/ITS)
Pulatifomu ya Amplicon (16S/18S/ITS) imapangidwa ndi zaka zambiri zakusanthula kwama projekiti osiyanasiyana, omwe amakhala ndi kusanthula koyambira ndi kusanthula kwamunthu payekha: kusanthula koyambira kumakhudza kusanthula kwakukulu kwa kafukufuku waposachedwa wa tizilombo tating'onoting'ono, zowunikira ndizolemera komanso zomveka, ndi zotsatira za kusanthula zimaperekedwa mu mawonekedwe a malipoti a polojekiti;Zomwe zili pakuwunika kwamunthu ndizosiyanasiyana.Zitsanzo zitha kusankhidwa ndipo magawo atha kukhazikitsidwa mosinthika malinga ndi lipoti lowunikira komanso cholinga cha kafukufuku, kuti mukwaniritse zomwe mukufuna.Mawindo opangira makina, osavuta komanso ofulumira.
