RNA yozungulira (circRNA) ndi mtundu wa RNA yosalemba, yomwe posachedwapa imapezeka kuti ikugwira ntchito yofunika kwambiri pamagulu olamulira omwe akukhudzidwa ndi chitukuko, kukana zachilengedwe, ndi zina zotero. Zosiyana ndi mamolekyu a RNA, mwachitsanzo mRNA, lncRNA, 3' ndi 5'. malekezero a circRNA amalumikizidwa palimodzi kuti apange mawonekedwe ozungulira, omwe amawapulumutsa ku chimbudzi cha exonuclease ndipo amakhala okhazikika kuposa RNA yambiri.CircRNA yapezeka kuti ili ndi ntchito zosiyanasiyana pakuwongolera ma jini.CircRNA imatha kuchita ngati ceRNA, yomwe imamanga miRNA mopikisana, yotchedwa miRNA siponji.CircRNA sequencing analysis platform imapatsa mphamvu circRNA kamangidwe ndi kusanthula mawu, kulosera chandamale ndi kusanthula pamodzi ndi mitundu ina ya mamolekyu a RNA.
Bioinformatics
