I-BMKGENE inikeze isevisi yokulandelana kwe-transcriptome ocwaningweni "I-cascade nanoreactor yokuthuthukisa ukwelashwa kwe-sonodynamic kumdlavuza we-colorectal nge-synergistic ROS augment kanye nokuvinjelwa kwe-autophagy", eyanyatheliswa ku-Nano Today.
Lolu cwaningo luhlose ukuthuthukisa ukusebenza kahle kwe-antitumor ye-sonodynamic therapy (SDT) kumdlavuza we-colorectal, ukuklama ngokunengqondo i-cascade nanoreactor ngokufaka i-sonosensitizer Ce6 kanye ne-autophagy inhibitor chloroquine ku-homologous tumor cell membrane-modified hollow polydopamine nanocarrier efakwe i-nanozy plati. (iqokwe njenge-CCP@HP@M).
Ukuhlaziywa kwe-RNA-seq kuphinde kwaqinisekisa i-apoptosis nezindlela ze-ferroptosis ezibandakanyeka ekwelashweni kwe-CCP@HP@M.Le nanoreactor ye-cascade izohlinzeka ngesu elithembisayo lokwengeza ukuqedwa kwe-SDT ngokumelene namathumba ngokushintshashintsha kwe-ROS kanye ne-autophagy.
Chofozalaphaukuze ufunde kabanzi mayelana nalesi sihloko.
Isikhathi sokuthumela: Sep-08-2023