I-RNA encane

Ama-RNA amancane awuhlobo lwe-RNA emfushane engafaki ikhodi enobude obuyisilinganiso esingu-18-30 nt, okuhlanganisa i-miRNA, i-siRNA ne-piRNA.Lawa ma-RNA amancane abikwe kakhulu ukuthi ahileleke ezinqubweni ezihlukahlukene zebhayoloji ezifana nokuwohloka kwe-mRNA, ukuvimbela ukuhumusha, ukwakheka kwe-heterochromatin, njll. Ukuhlaziywa kokulandelana kwe-SmallRNA kusetshenziswe kabanzi ezifundweni zokuthuthukiswa kwezilwane/izitshalo, izifo, igciwane, njll. I-RNA encane. inkundla yokuhlaziya ukulandelana iqukethe ukuhlaziywa okujwayelekile kanye nokumbiwa kwedatha okuthuthukisiwe.Ngokwesisekelo sedatha ye-RNA-seq, ukuhlaziya okujwayelekile kungafinyelela ukuhlonza nokubikezela kwe-miRNA, ukubikezela kofuzo okuhlosiwe kwe-miRNA, isichasiselo nokuhlaziywa kwenkulumo.Ukuhlaziywa okuthuthukile kuvumela ukusesha nokukhipha i-miRNA ngendlela oyifisayo, ukukhiqizwa komdwebo we-Venn, i-miRNA kanye nokwakhiwa kwenethiwekhi yofuzo oluqondiwe.