DNA methylation yana ɗaya daga cikin gyare-gyaren epigenetic da aka yi nazari sosai.Yana taka muhimmiyar rawa a cikin kwanciyar hankali na kwayoyin halitta, tsarin rubutun kwayoyin halitta, da haɓaka halaye.An ƙayyade rubutun kwayoyin halitta ta hanyar matsayin methylation, tare da ƙananan matakan methylation da ke hade da maganganun kwayoyin halitta da kuma matakan methylation mai girma da ke hade da yin shiru.
Haɗe-haɗe-haɗe-haɗe-haɗe-haɗe bisulfite sequencing (WGBS) da RNA-seq bayanai yana ba da damar yin cikakken bincike na kwayoyin halitta da kwafi, bayyana hanyoyin sarrafa kwayoyin halitta, da gano sabbin hanyoyin nazarin halittu da alamun halittu.Za a iya kafa haɗin kai tsakanin bayanan bayanan da aka rubuta da kuma methylation bisa ga kwayoyin halitta, haɗawa duka biyun bayanan ta amfani da kwayoyin halitta a matsayin gada.
Wannan bincike yana taimakawa wajen fahimtar alaƙar da ke tsakanin DNA methylation da maganganun kwayoyin halitta, gano kwayoyin halittar da methylation ya rinjayi, da kuma bincika tasirin aikin ƙasa.
Jin kyauta don tuntuɓar BMKGENE don ƙarin haske mara misaltuwa game da binciken epigenetic.
Lokacin aikawa: Dec-05-2023