I-BMKGENE ibonelele ngolandelelwano kunye neenkonzo zokuhlalutya ze-16S rDNA amplicon kunye ne-metabolomics kuphononongo olunesihloko esithi "I-vitamin B1 yoomama yinto emisela ikamva lokuqulunqwa kwe-follicle yokuqala kwinzala", eyapapashwa kwiNdalo yoNxibelelwano.
Uphononongo lwafumanisa ukuba kwiimpuku, ukutya okunamafutha aphezulu kamama ngexesha lokukhulelwa kuphazamisa ukugcinwa kwe-ovarian primordial follicle pool kwinzala yabasetyhini, eyayihamba kunye nokungasebenzi kakuhle kwe-mitochondrial yeeseli zentsholongwane.Oku kwakungenxa yokuhla kwe-vithamini B1 enxulumene ne-maternal gut microbiota, eyabuyiselwa nge-vitamin B1.
Isishwankathelo, uphononongo lugxininisa indima yokutya okunamafutha aphezulu kumama ekuphembeleleni inzala ye-oogenic kwaye iphakamisa ukuba i-vitamin B1 ingaba yindlela yonyango ethembisayo yokukhusela impilo yenzala.
CofaAphaukufunda ngakumbi malunga nesi sifundo.
Ixesha lokuposa: Dec-20-2023