i-lncrna

IiRNA ezinde ezingabhalisiyo iikhowudi (i-lncRNA) zii-RNA ezinde kunee-nucleotides ezingama-200 ezinamandla okubhala ikhowudi aphantsi kodwa ezinemisebenzi ebalulekileyo yokulawula. Umbhobho we-BMKCloud lncRNA wenzelwe ukuhlalutya iilayibrari eziphelelwe yi-rRNA ezine-genome yereferensi esemgangathweni ophezulu, eneenkcukacha ezichanekileyo, ngokuhlalutya ukubonakaliswa kwe-lncRNA kunye ne-mRNA kunye. Emva kokunciphisa ukufunda kunye nokulawula umgangatho, ii-reads zihambelana ne-genome yereferensi ukuze kuhlanganiswe ii-transcripts, kwaye uhlalutyo lwesakhiwo se-gene olulandelayo lubonisa ukuhlanganiswa okuthe tye kunye nee-genes ezintsha. Ii-transcripts zichongwa njengee-mRNA okanye ii-lncRNA, kwaye uhlalutyo lokubonakaliswa okuhlukeneyo luchonga ii-lncRNA ezichazwe ngokwahlukileyo, iithagethi zazo kunye nee-genes ezichazwe ngokwahlukileyo (ii-DEGS). Zombini ii-DEG kunye neethagethi ze-lncRNA ezichazwe ngokwahlukileyo zineenkcukacha ezichanekileyo ukuze kufunyanwe iindidi zokusebenza ezicebileyo.