BMKGENE muab spatial transcriptomics sequencing cov kev pab cuam rau txoj kev tshawb no: ib tug muaj peev xwm Drosophila homologue ntawm mammalian adhesion GPCRs, yog koom nyob rau hauv antitumor tshuaj tiv thaiv rau txhaj oncogenic hlwb nyob rau hauv yoov, uas tau luam tawm nyob rau hauv PNAS, mthl1.
Nyob rau hauv txoj kev tshawb no, cov neeg laus cov yoov tau txhaj tshuaj OCs, thiab spatial transcriptome sequencing ntawm cov yoov khov yog ua.Kev txhaj tshuaj ntawm OCs rau hauv cov txiv neej laus yoov ua rau muaj zog transcriptomic teb nyob rau hauv tus tswv yoov featuring nyob rau hauv tshwj xeeb genes encoding bona fide G-coupled proteins, ntawm uas cov noob rau methuselah-zoo li 1 yog ib qho tseem ceeb.
Los ntawm kev sib xyaw ua ke ntawm cov noob caj noob ces ntawm mthl1 gene (poob ntawm kev ua haujlwm thiab overexpression ntawm mthl1), tau sau tseg tias qhov tseeb no noob muaj cov nyhuv antiproliferative.Tsis tas li ntawd, qhia tau tias mthl1 tswj kev qhia ntawm ntau cov noob coding rau chemoreceptors thiab cov noob cuam tshuam hauv kev tswj hwm kev loj hlob.Deciphered cov kev tiv thaiv mechanisms ntawm yoov tawm tsam cov qog nyob rau hauv tsis muaj adaptive tiv thaiv.
Nyem qhov no kom paub ntau ntxiv txog qhov kev kawm no
Post lub sij hawm: Aug-10-2023