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Featured Publication—Ampicillin-controlled glucose metabolism manipulates the transition from tolerance to resistance in bacteria
Our bacterial whole genome sequencing and analysis services played a crucial role in a study published in Science Magazine. The research reveals that ampicillin-controlled glucose metabolism manipulates the transition from tolerance to resistance in bacteria. Glucose abundance decreases progress...
Featured Publication—Synthetic bacterial consortia transplantation for the treatment of Gardnerella vaginalis-induced bacterial vaginosis in mice
News in microbiome research! A recent publication in Microbiome(BMC journal) investigates Synthetic Bacterial Consortia Transplantation (SBCT) for Gardnerella vaginalis-induced bacterial vaginosis in mice, with valuable 16S amplicon sequencing and analysis services provided by BMKGENE The study ...
Featured Publication—Genetic linkage analysis of stable QTLs in Gossypium hirsutum RIL population revealed function of GhCesA4 in fiber development
Youlu Yuan and his team at the Chinese Academy of Agricultural Sciences (CAAS) Cotton Research Institute have successfully created a high-density genetic map using upland cotton’s recombinant inbred line (RIL) population. The team also identified crucial genes that are negatively correlate...
Featured Publication—Gut microbiota-derived metabolites facilitate melatonin’s neuroprotective properties in sleep deprivation-induced cognitive impairment
BMKGENE provided microbial amplicon sequencing and non-target metabolome testing services for this study “Gut microbiota-derived metabolites facilitate melatonin’s neuroprotective properties in sleep deprivation-induced cognitive impairment,” which delves into the findings of m...
Featured Publication—Targeting hnRNPC suppresses thyroid follicular epithelial cell apoptosis and necroptosis through m6A-modified ATF4 in autoimmune thyroid disease
The study published in Pharmacological Research titled “Targeting hnRNPC suppresses thyroid follicular epithelial cell apoptosis and necroptosis through m6A-modified ATF4 in autoimmune thyroid disease” utilized various sequencing techniques such as single-cell transcriptome, whole tr...
Featured Publication—Identification of a novel role for TL1A/DR3 deficiency in acute respiratory distress syndrome that exacerbates alveolar epithelial disruption
Acute Respiratory Distress Syndrome (ARDS) is an acute respiratory disease involving blood-gas barrier dysfunction. ARDS is primarily characterized by pulmonary edema caused by hyperpermeability of the vascular endothelium and alveolar epithelium. The article titled “Identification of a no...
Featured Publication—Mapping and functional dissection of the rumpless trait in Piao chicken identifies a causal loss of function mutation in the novel gene Rum
Another successful case of BMKGENE has been published online! On December 9, 2023, the article titled “Mapping and functional dissection of the rumpless trait in Piao chicken identifies a causal loss of function mutation in the novel gene Rum” was published in Molecular Biology and...
Featured Publication—Maternal vitamin B1 is a determinant for the fate of primordial follicle formation in offspring
BMKGENE provided sequencing and analysis services of 16S rDNA amplicon and metabolomics for the study titled “Maternal vitamin B1 is a determinant for the fate of primordial follicle formation in offspring”, which was published in Nature Communications. The study found that in mice,...
Featured Publication—Allele-defined genome reveals biallelic differentiation during cassava evolution
BMKGENE has extensive experience in this area, here is a featured publication for Cassava published on Molecular Plant. Haplotype analysis can provide a foundation for understanding the genetic mechanisms underlying important shape formations in a species. Most diploid genome assemblies ignore d...
Featured Publication—Different roles of host and habitat in determining the microbial communities of plant-feeding true bugs
BMKGENE provided full-length amplicon sequencing services for the study titled “Different roles of host and habitat in determining the microbial communities of plant-feeding true bugs” published in Microbiome. The study aimed to explore the symbiotic relationships between plant-feeding true bug...
Featured Publication—The nanoformula of zoledronic acid and calcium carbonate targets osteoclasts and reverses osteoporosis
BMKGENE provided long non-coding RNA sequencing services for the article “The nanoformula of zoledronic acid and calcium carbonate targets osteoclasts and reverses osteoporosis”, which was published in Biomaterials, herein, an OCs’ microenvironment-responsive nanoplatform-HMCZP is de...
Featured Publication—Comparative analysis of PacBio and ONT RNA sequencing methods for Nemopilema Nomurai venom identification
BMKGENE provided full-length transcriptome sequencing services using PacBio and ONT technologies for a study titled “Comparative analysis of PacBio and ONT RNA sequencing methods for Nemopilema Nomurai venom identification”, which was published in the journal Genomics. The study aimed...
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