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circ-rna

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Circ-RNA

Circular RNA(circRNA) is a type of non-coding RNA, which are recently found to play vital role in regulatory networks involved in developing, environmental resistance, etc. Distinct from linear RNA molecules, e.g. mRNA, lncRNA, 3′ and 5′ ends of circRNA are joined together to form a circular structure, which save them from digestion of exonuclease and are more stable than most of linear RNA. CircRNA have been found to have diverse functions in regulating gene expression. CircRNA can perform as ceRNA, which binds miRNA competitively, known as miRNA sponge. CircRNA sequencing analysis platform empowers circRNA structure and expression analysis, target prediction and joint analysis with other types of RNA molecules

Bioinformatics

3-1-13-1-12

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