Genome-wide Association Analysis
1.Service Advantages
● Abundant Project Cases: since its establishment in 2009, BMKGENE has completed hundreds of species projects in population GWAS research, assisted researchers to publish more than 100 articles, and the cumulative impact factor reached 500.
● Professional analysts.
● Short analysis cycle.
● Accurate data mining.
2. Service Specifications
|
Type |
Population Scale |
Sequencing strategy and depth
|
| SLAF-GWAS | Sample number ≥200 | Genome size < 400M, with ref-genome, WGS is recommended |
|
Genome size ≤ 1G, 100K Tags and 10X |
||
|
1G ≤ Genome size ≤ 2G, 200K Tags and 10X |
||
|
Genome size > 2G, 300K Tags and 10X |
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|
WGS-GWAS |
Sample number ≥200 |
10X for each sample |
3. Material Selection
Different varieties, subspecies, landraces/genebanks/mixed families/wild resources
Different varieties, subspecies, landraces
Half-sib family/full-sib family/wild resources
4. Bioinformation Analysis
● Genome-wide association analysis
● Analysis and screening of significant SNP
● Functional annotation of candidate gene
5. Service Work Flow
Experiment design
Sample delivery
RNA extraction
Library construction
Sequencing
Data analysis
After-sale services
a. Phenotype QC
Frequency distribution histogram
Phenotype statistics
b. Association analysis (Model: GEMMA, FaST-LMM, EMMAX)
Q-Q Plot
Manhattan Plot
|
Year |
Journal |
IF |
Title |
|
2022 |
NC |
17.69 |
Genomic basis of the giga-chromosomes and giga-genome of tree peony Paeonia ostii |
|
2015 |
NP |
7.43 |
Domestication footprints anchor genomic regions of agronomic importance in soybeans |
|
2018 |
MP |
9.32 |
Whole-genome resequencing of a world-wide collection of rapeseed accessions reveals genetic basis of their ecotype divergence |
|
2022 |
HR |
7.29 |
Genome-wide association analysis provides molecular insights into the natural variation of watermelon seed size |
