circ-rna

Circular RNA (circRNA) imhando yeRNA isiri-coding, iyo ichangobva kuwanikwa inobata basa rinokosha mukugadzirisa masangano anobatanidzwa mukuvandudza, kudzivirira kwezvakatipoteredza, nezvimwewo. migumo ye circRNA inobatanidzwa pamwe chete kuti iite denderedzwa chimiro, iyo inovaponesa kubva pakugayiwa kwe exonuclease uye yakagadzikana kupfuura yakawanda yemutsara RNA.CircRNA yakawanikwa iine mabasa akasiyana-siyana mukugadzirisa mataurirwo ejene.CircRNA inogona kuita se ceRNA, inosunga miRNA mumakwikwi, inozivikanwa semiRNA sponge.CircRNA sequencing yekuongorora chikuva inopa simba circRNA chimiro uye ongororo yekutaura, kufanotaura kwechinangwa uye kuongororwa kwakabatana nemamwe marudzi emamorekuru eRNA.