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Proteomics
Proteomics involves the applications of technologies for the quantification of overall proteins present content of a cell, tissue or an organism. Proteomics-based technologies are utilized in various capacities for different research settings such as detection of various diagnostic markers, candidates for vaccine production, understanding pathogenicity mechanisms, alteration of expression patterns in response to different signals and interpretation of functional protein pathways in different diseases. At present, quantitative proteomics technologies are mainly divided into TMT, Label Free and DIA quantitative strategies.
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Metabolomics
The metabolome is the terminal downstream product of the genome and consists of the total complement of all the low-molecular-weight molecules (metabolites) in a cell, tissue, or organism. Metabolomics aims to measure a wide breadth of small molecules in the context of physiological stimuli or disease states. Metabolomics methodologies fall into two distinct groups: non-targeted metabolomics, an intended comprehensive analysis of all the measurable analytes in a sample including chemical unknowns using GC-MS/LC-MS, and targeted metabolomics, the measurement of defined groups of chemically characterized and biochemically annotated metabolites.
