Lihlahisoa

Genome-wide Association Analysis

Boithuto ba Genome-wide Association (GWAS) bo ikemiselitse ho khetholla mefuta e fapaneng ea liphatsa tsa lefutso (genotype) e amanang le litšobotsi tse itseng (phenotype).Boithuto ba GWAS bo batlisisa matšoao a liphatsa tsa lefutso tse tšelang palo e kholo ea batho ka bomong le ho bolela esale pele mekhatlo ea genotype-phenotype ka tlhahlobo ea lipalo maemong a baahi.E sebelisitsoe haholo lipatlisisong tsa mafu a batho le merafo e sebetsang ea liphatsa tsa lefutso ka litšobotsi tse rarahaneng tsa liphoofolo kapa limela.

Iteanye le rona

Lintlha tsa Tšebeletso

Sephetho sa Demo

Phatlalatso e Featured

1.Melemo ea Ts'ebeletso

● Melato e Meholo ea Merero: Ho tloha ha e thehoa ka 2009, BMKGENE e phethetse merero ea mefuta e makholo ho lipatlisiso tsa GWAS ea baahi, e thusitse bafuputsi ho hatisa lingoliloeng tse fetang 100, 'me phello e akaretsang e fihlile ho 500.
● Bahlahlobisisi ba litsebi.
● Potoloho e khutšoanyane ea tlhahlobo.
● Ho rafa data ho nepahetseng.

2. Litlhaloso tsa Tšebeletso

Mofuta	Palo ea Baahi	Leano la tatellano le botebo
SLAF-GWAS	Nomoro ea mohlala ≥200	Saese ea genome <400M, e nang le ref-genome, WGS e khothaletsoa
		Boholo ba Genome ≤ 1G, 100K Tags le 10X
		1G ≤ Boholo ba Genome ≤ 2G, 200K Tags le 10X
		Boholo ba Genome> 2G, 300K Tags le 10X
WGS-GWAS	Nomoro ea mohlala ≥200	10X bakeng sa sampole ka 'ngoe

3. Khetho ea Lintho

Mefuta e fapaneng e fapaneng, lihloliloeng, li-landraces / libanka tsa liphatsa tsa lefutso / malapa a tsoakiloeng / lisebelisoa tse hlaha

Mefuta e fapaneng, li-subspecies, landraces

Half-sib family/full-sib family/wild resources

4. Tlhahlobo ea Bioinformation

● Tlhahlobo ea mokhatlo oa Genome-wide
● Ho hlahloba le ho hlahloba SNP ea bohlokoa
● Tlhaloso e sebetsang ea mofuta oa mokhethoa

5. Phallo ea Mosebetsi oa Tšebeletso

Moqapi oa liteko

Mohlala oa thomello

Tlhahiso ea RNA

Kaho ea laebrari

Tatelano

Tlhahlobo ea lintlha

Litšebeletso tsa ka mor'a thekiso

E fetileng: Sequloana se le seng sa RNA Sequencing

E 'ngoe:

a.Phenotype QC

Hangata histogram ea kabo

Lipalopalo tsa Phenotype

b.Tlhahlobo ea mokhatlo (Mohlala: GEMMA, FAST-LMM, EMMAX)

Lethathamo la lintlha tsa QQ

Manhattan Plot

Selemo	Journal	IF	Sehlooho
2022	NC	17.69	Genomic motheo oa giga-chromosomes le giga-genome ea sefate peony Paeonia ostii
2015	NP	7.43	Mehato ea lapeng e tiisa libaka tsa genomic tsa bohlokoa ba temo ea soya
2018	MP	9.32	Requencing ea liphatsa tsa lefutso kaofela tsa pokello ea lefats'e ka bophara ea lipese tsa liphoofolo tse rutoang li senola motheo oa liphatsa tsa lefutso tsa phapang ea bona ea ecotype.
2022	HR	7.29	Tlhahlobo ea Genome-wide Association e fana ka leseli la limolek'hule mabapi le phapang ea tlhaho ea boholo ba peo ea lehapu